Active — Not RecruitingNot Applicable

Supporting Treatment Access and Recovery Through Linkage and Support

United States208 participantsStarted 2023-05-24

Plain-language summary

This 3-year Hybrid Type 1 study will randomize 208 people with co-occurring substance use and mental health disorders (COD) referred from the Worcester Hub. This study seeks to evaluate the effectiveness of MISSION, a multi-component team approach, versus linkage with a Peer Specialist on improving outcomes among individuals with CODs. We expect that individuals receiving MISSION versus linkage only will show greater improvement in treatment engagement, substance use, and mental health outcomes. This study will also concurrently conduct a process evaluation to inform sustainability and future implementation of such interventions.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Are 18 or older; * Have a COD (1 or more substance use disorders (e.g., alcohol and illicit substances), and a mental health disorder (including depression, anxiety, trauma related disorders, bipolar, and/or schizophrenia); * Are in the Hub; and * Are not engaged in other ongoing multi-component treatment for COD with a behavioral health treatment provider or have not seen their provider for at least 3 months. Exclusion Criteria: * We will exclude individuals who are acutely psychotic, acutely suicidal with a plan, or homicidal * Or with concurrent severe alcohol use disorder or high dose benzodiazepine requiring detoxification.

What they're measuring

Self-report opioid use and other substance use

Timeframe: Baseline

Self-report opioid use and other substance use

Timeframe: 3-months

Self-report opioid use and other substance use

Timeframe: 6-months

Self-report opioid use and other substance use

Timeframe: 9-months

Mental Health Functioning

Timeframe: Baseline

Mental Health Functioning

Timeframe: 3-months

Mental Health Functioning

Timeframe: 6-months

Mental Health Functioning

Timeframe: 9-months

PTSD Symptoms

Timeframe: Baseline

Trial details

NCT IDNCT05713695

SponsorUniversity of Massachusetts, Worcester

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-09

View on ClinicalTrials.gov More Mental Health Disorders trials

Plain-language summary

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Self-report opioid use and other substance use

Timeframe: Baseline

Self-report opioid use and other substance use

Timeframe: 3-months

Self-report opioid use and other substance use

Timeframe: 6-months

Self-report opioid use and other substance use

Timeframe: 9-months

Mental Health Functioning

Timeframe: Baseline

Mental Health Functioning

Timeframe: 3-months

Mental Health Functioning

Timeframe: 6-months

Mental Health Functioning

Timeframe: 9-months

PTSD Symptoms

Timeframe: Baseline