CompletedNot Applicable

Experimental Techniques for Early Identification of Autism

Italy100 participantsStarted 2021-07-19

Plain-language summary

This project deals with essential challenges in the context of Autism Spectrum Disorder, benefiting from a longitudinal design in infancy and a cutting-edge electroencephalogram/eye-tracking integrated approach. The investigators will focus on multisensory audiovisual integration to identify early markers of autism in infants at-risk for autism. The investigators will characterize early derailments from the typical developmental trajectories to identify critical "time windows" and better describe the heterogeneity of autism.

Who can participate

Age range6 Months – 36 Months

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Infants aged between 6 and 36 months * Toddlers at elevated likelihood of developing autism because siblings of children with autism Exclusion Criteria: * gestational age \<36 weeks * Griffiths general quotient \< 70 * presence of major complications in pregnancy and/or delivery likely to affect brain development * presence of neurological deficits, dysmorphic markers, or other medical conditions

What they're measuring

Cognitive outcome of standardized tests

Timeframe: age 36 months

Socio-communicative outcome of standardized tests

Timeframe: age 36 months

Sensory outcome of standardized tests

Timeframe: age 36 months

Change of electroencephalografic theta power and looking behavior during development

Timeframe: at 6, 12, 18 and 24 months

Trial details

NCT IDNCT05712512

SponsorIRCCS Eugenio Medea

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2023-03-31

View on ClinicalTrials.gov More Autism Spectrum Disorder trials