CompletedNot Applicable

Effect of Waterpipe Size on Smoking Behavior and Exposures

United States40 participantsStarted 2022-04-22

Plain-language summary

The goal of this clinical trial is to learn how waterpipe (WP) size affects smoking behavior, toxicant exposure, and subjective experiences in young adult WP smokers (ages 21-39). The main questions it aims to answer are: * Does WP size change puffing behavior? * Does WP size change exposure to nicotine and carbon monoxide? * Does WP size change perceptions of harm, satisfaction, craving, or withdrawal? Participants will smoke small, medium, and large WPs in separate sessions. Researchers will measure puffing behavior, saliva nicotine, exhaled carbon monoxide, and survey responses before and after each session.

Who can participate

Age range

21 Years – 39 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * regular waterpipe smokers (smoking at least once a week for the past 6 months) * generally healthy and * able to provide written informed consent; and willing to attend the 3 lab sessions Exclusion Criteria: * history of chronic diseases such as diabetes, high blood cholesterol, hepatic disease * respiratory chronic diseases * cardiovascular diseases including low or high blood pressure (BP)

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Waterpipe Evaluation Scale

Timeframe: Immediately after the exposure (smoking)

Duke Sensory Questionnaire

Timeframe: Immediately after the exposure (smoking)

Harm Perception Questionnaire

Timeframe: Immediately after the exposure (smoking)

Saliva Nicotine

Timeframe: Immediately after the exposure (smoking)

Puff Topography: Smoking Time

Timeframe: During the exposure (smoking), up to 45 mins

Puff Topography: Cumulative Puff Time

Timeframe: During the exposure (smoking), up to 45 mins

Puff Topography: Puff Duration

Timeframe: During the exposure (smoking), up to 45 mins

Trial details

NCT IDNCT05705375

SponsorThe University of Texas at Arlington

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-02-28

Results submitted2025-06-27

View on ClinicalTrials.gov More Waterpipe Size trials

Plain-language summary

Who can participate

Age range

21 Years – 39 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Waterpipe Evaluation Scale

Timeframe: Immediately after the exposure (smoking)

Duke Sensory Questionnaire

Timeframe: Immediately after the exposure (smoking)

Harm Perception Questionnaire

Timeframe: Immediately after the exposure (smoking)

Saliva Nicotine

Timeframe: Immediately after the exposure (smoking)

Puff Topography: Smoking Time

Timeframe: During the exposure (smoking), up to 45 mins

Puff Topography: Cumulative Puff Time

Timeframe: During the exposure (smoking), up to 45 mins

Puff Topography: Puff Duration

Timeframe: During the exposure (smoking), up to 45 mins