WithdrawnNot Applicable

Effectiveness of Outpatient Intravenous Diuretic Therapy for Treatment of Worsening Heart Failure (OUTPATIENT-WHF)

Stopped: Study no longer moving forward

United States0Started 2023-03-27

Plain-language summary

The purpose of the OUTPATIENT-WHF study is to characterize the effectiveness of outpatient intravenous diuretic therapy as a treatment for worsening heart failure.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. ≥18 years of age
✓. Presentation to a Duke outpatient clinic with heart failure requiring IV diuretics, as per clinician judgement
✓. Able to provide signed informed consent
✓. Successful completion of EuroQOL-5 dimensions survey

Exclusion criteria

✕. Managing clinician without equipoise for initial outpatient treatment strategy versus initial hospitalization-based treatment strategy for heart failure, and decline to accept randomization.
✕. Patient without equipoise for initial outpatient treatment strategy versus initial hospitalization-based treatment strategy for heart failure, and decline to accept randomization.
✕. History of left ventricular assist device or heart transplantation
✕. End-stage kidney disease requiring chronic dialysis therapy
✕. New diagnosis of heart failure
✕. Pregnant or breast-feeding
✕. Fever \>101.0 degrees Fahrenheit at screening
✕. Any other condition that in the judgment of the investigator would jeopardize the patient's compliance with the study protocol

What they're measuring

Days alive and out of hospital

Timeframe: 30 days

Trial details

NCT IDNCT05704595

SponsorDuke University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-04

View on ClinicalTrials.gov More Heart Failure trials