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Application of "Heidelberg Triangle" Dissection in Pancreatoduodenectomy and Distal Pancreatectomy

China200 participantsStarted 2023-03-01

Plain-language summary

Aim of the study : To evaluate the effect and safety of "Heidelberg Triangle" dissection (TRIANGLE operation) combined with Pancreatoduodenectomy or Distal Pancreatectomy on the prognosis of pancreatic cancer and periampullary cancer . Methods : Patients who underwent pancreatoduodenectomy or Distal Pancreatectomy between 01 September 2016 and 30 December 2022 will be included in this retrospective analysis. 3D reconstruction is performed with preoperative enhanced CT, then the region of "Heidelberg Triangle" is categorized . The operation is completed by the same operation team. According to the operation mode, patients were divided into TRIANGLE group and non-TRIANGLE group and And followed up until recurrence, death or missed.

Who can participate

Age range18 Years – 90 Years

SexALL

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Inclusion criteria

✓. Patients diagnosed by preoperative imaging and auxiliary examination as resectable or borderline resectable pancreatic malignant tumor or periampullary carcinoma who underwent pancreatoduodenectomy or distal pancreatectomy, with or without TRIANGLE operation.
✓. Patients who have no serious abnormalities of blood system, heart and lung function and immune deficiency and can tolerate surgery.
✓. Be able to comply with the research visit plan and other program requirements

Exclusion criteria

✕. Patients accompanied by other systemic malignancies.
✕. Central nervous system disease, mental disease, unstable angina pectoris, congestive heart failure, serious arrhythmia and other uncontrollable serious diseases, unable to tolerate surgery.
✕. Pregnant and lactating women.
✕. Any condition that may impair the safety of patients or the integrity of research data, including serious medical risk factors, medical conditions, and laboratory abnormalities.

What they're measuring

Recurrence free survival (RFS)

Timeframe: up to 72 months

Trial details

NCT IDNCT05703581

SponsorFudan University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-01-01

Contact for this trial

Chongyi Jiang, PhD

+86-18101802916 jiangzhongyi9@126.com

View on ClinicalTrials.gov More Pancreatoduodenectomy trials