RecruitingNot Applicable

Imaging the Pathogenesis of Cerebral Small Vessel Disease

United States50 participantsStarted 2022-11-08

Plain-language summary

Cerebral small vessel disease (CSVD) can lead to vascular cognitive impairment and dementia (VCID). The hallmark of CSVD is the appearance and progression of white matter hyperintensities (WMH) on MRI. The goal of this study it to recruit and follow individuals at risk for WMH progression and use serial MRI scanning to gain insights into the pathogenesis of CSVD.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Clinical or radiographic evidence of ischemic stroke * One vascular risk factor (hypertension, hyperlipidemia, or diabetes) * Evidence of cerebral small vessel disease on MRI Exclusion Criteria: * Inability to complete 3 research MRI scans over 1.25 years

What they're measuring

Progression of cerebral small vessel disease

Timeframe: 1 year

Trial details

NCT IDNCT05703386

SponsorJohns Hopkins University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-03-31

Contact for this trial

Sera Chase

410-502-5355 schase15@jh.edu

View on ClinicalTrials.gov More Ischemic Stroke trials