Lactate Profile and Fat Oxidation During Exercise (NCT05703100) | Clinical Trial Compass
CompletedNot Applicable
Lactate Profile and Fat Oxidation During Exercise
Spain19 participantsStarted 2023-01-28
Plain-language summary
The goal of this clinical trial is to test whether changes in lactate kinetics during exercise (due to glycogen depletion or hyperthermia) alter the pattern of fat oxidation during a maximal incremental cycle ergometer test in healthy young active people. The main questions it aims to answer are:
* Will a rightward shift in lactate kinetics, induced by a previous glycogen depletion, produce a rightward shift in fat oxidation?
* Will a leftward shift in lactate kinetics due to an increase in ambient temperature produce a leftward shift in fat oxidation?
Participants will perform three maximal incremental tests in three different conditions:
* one in the control condition;
* one with glycogen depletion;
* and one with ambient heat (the latter two in randomized, counterbalanced order).
Who can participate
Age range
18 Years – 40 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Perform endurance training with a volume of between 3 and 12h/week
* In women, having regular menstrual cycles (25-35 days length)
* In women, being able to perform the test without menstrual discomfort or pain and without having taken anti-inflammatory or analgesic drugs
Exclusion Criteria:
* Suffering from any previous disease, disorder or ailment that could affect the results of the study variables
* Smoking
* In women, using any type of hormonal contraceptive
* In women, having heavy menstrual bleeding, detected with the menstrual bleeding questionnaire proposed by Wyatt et al. (2001)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Blood lactate concentration
Timeframe: Through study completion, an average of 5 months
2
Fat oxidation
Timeframe: Through study completion, an average of 5 months