RecruitingNot Applicable

A Study to Analyze the Role of Sympathetic Nervous System in Spontaneous Coronary Artery Dissection

United States50 participantsStarted 2023-06-01

Plain-language summary

The purpose of this research is to compare sympathetic function (flight or fight system) and arterial health including structure and mechanics of participants with history of spontaneous coronary artery dissection (SCAD) to age and sex matched control participants.

Who can participate

Age range18 Years

SexFEMALE

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Inclusion Criteria: * For SCAD patients: history of SCAD as confirmed by coronary angiography or cardiac computed tomography angiography * For controls: no cardiac disease history Exclusion Criteria: * Pregnancy * Known or suspected unstable cardiac condition within 4 weeks of the study * Active treatment with anticoagulation or dual antiplatelet therapy * Prisoner

What they're measuring

Arterial thickness

Timeframe: Baseline

Arterial stiffness

Timeframe: Baseline

Baroreflex sensitivity

Timeframe: Baseline

Sympathetic response to stress

Timeframe: Baseline

Trial details

NCT IDNCT05699200

SponsorMayo Clinic

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-08

Contact for this trial

Pamela Engrav

507-255-6938 Engrav.Pamela@mayo.edu

View on ClinicalTrials.gov More Spontaneous Coronary Artery Dissection trials