Investigations Into Sepsis-associated Acute Kidney Injury

Inclusion Criteria sepsis group: * Sepsis diagnosed or suspected * Normal premorbid serum creatinine measured or anticipated (if data are not available) * Normovolemia as indicated by a pulse pressure variation less than 12% Comparator group * Previously healthy individuals scheduled for laparoscopic colon cancer resection * Normal creatinine levels within 3 months before admittance to hospital. * Patients admitted to the intensive care unit with sepsis diagnosed or suspected * Previously healthy patients listed for elective colon cancer surgery Exclusion Criteria: \-