Management of DE With IPL in Combination With DQS

Inclusion Criteria: * Age ≥18 years * Consenting participants * Able and willing to comply with the treatment/follow-up schedule * Bilateral signs and symptoms of dry eye disease: (i) Ocular Surface Disease Index (OSDI) questionnaire ≥13, (ii) Non-invasive tear break-up (NITBUT) ≤ 5 seconds, (iii) conjunctival staining score (CS) ≥3 points. The presence of two or more criteria was used to establish a positive DE diagnosis based on the 2016 Asia Dry Eye Society criteria Exclusion Criteria: * A recent history (past 30 days) of topical ophthalmic medication use, including antibiotics, steroids, non-steroidal anti-inflammatory drugs, or required the chronic use of topical ophthalmic medications. * Eyelids or intraocular tumors. * Active allergy or infection, or inflammatory disease may prevent the subjects from completing the study at the ocular surface. * Any structural changes in the lacrimal passage * Glaucoma * Diabetes or other systemic, dermatologic, or neurologic diseases that affect the health of the ocular surface. * Use of any systemic anti-inflammatory drugs or medication that may interfere with tear production, such as antianxiety, anti-depressive, and antihistamine medications, within three months. * Pregnancy or breastfeeding * Contact lenses wearers.