CompletedNot Applicable

Different Crystalloid Coload Volumes on the 90% ED of Norepinephrine

China90 participantsStarted 2023-03-21

Plain-language summary

The purpose of this study is to investigate the effect of different crystalloid coload volumes on the 90% effective dose of prophylactic norepinephrine infusions for preventing postspinal anesthesia hypotension during cesarean section.

Who can participate

Age range18 Years – 45 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 18-45 years * Primipara or multipara * Singleton pregnancy ≥37 weeks * American Society of Anesthesiologists physical status classification I to II * Scheduled for cesarean section under spinal anesthesia Exclusion Criteria: * Body height \< 150 cm * Body weight \> 100 kg or body mass index (BMI) ≥ 40 kg/m2 * Eclampsia or chronic hypertension or baseline blood pressure ≥180 mmHg * Hemoglobin \< 7g/dl * Fetal distress, or known fetal developmental anomaly

What they're measuring

ED50 and ED90

Timeframe: 1-15 minutes after spinal anesthesia

Trial details

NCT IDNCT05690334

SponsorGeneral Hospital of Ningxia Medical University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-06-16

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