UnknownEarly Phase 1

Effect of Bromelain Versus Calcium Hydroxide as an Intracanal Medication on the Intensity of Postoperative Pain and Bacterial Load Reduction in Necrotic Single Rooted Lower Premolars

30 participantsStarted 2023-02-10

Plain-language summary

the aim of the study is to compare the effect of bromelain vs calcium hydroxide as intracanal medication on intensity of pain and bacterial load in necrotic single lower premolars

Who can participate

Age range25 Years – 50 Years

SexALL

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Inclusion criteria

✓. Patients who are free from any physical or mental handicapping condition with no underlying systemic disease (ASA I or II) .
✓. Age between 25-50 years old.
✓. Males \& Females.
✓. Patients who can understand pain scale and can sign the informed consent.
✓. Mandibular Single rooted premolars, having single root canal:

What they're measuring

postoperative pain intensity

Timeframe: 6 hours post-instrumentation

postoperative pain intensity

Timeframe: 12 hours post-instrumentation

postoperative pain intensity

Timeframe: 24 hours post-instrumentation

postoperative pain intensity

Timeframe: 48 hours post-instrumentation

Trial details

NCT IDNCT05687760

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-02-10

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