Active — Not RecruitingPhase 3

Intensive Postpartum Antihypertensive Treatment

United States60 participantsStarted 2023-09-01

Plain-language summary

The long-term goal of our work is to evaluate the effect of intensive postpartum blood pressure control on maternal cardiovascular health, risk of chronic hypertension, and reversal of vascular dysfunction generated by hypertensive disorders of pregnancy, thus attenuating the lifelong trajectory of cardiovascular disease risk.

Who can participate

Age range18 Years – 45 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * HDP diagnosis (gestational hypertension or preeclampsia) according to ACOG guidelines * Postpartum day 0-3 and prior to discharge * Able to communicate in English or in Spanish * Age 18 - 45 Exclusion Criteria: * Pre-gestational hypertension * Pre-gestational diabetes ( type 1 or type 2) * Intent to transfer postpartum to an outside institution of the participating centers * Known allergy to nifedipine or other significant contraindication to nifedipine * Inability or unwillingness to provide informed consent

What they're measuring

Feasibility in randomization

Timeframe: 12 months postpartum

Feasibility in recruitment

Timeframe: 12 months postpartum

Feasibility in retention

Timeframe: 12 months postpartum

Contamination

Timeframe: 12 months postpartum

Trial details

NCT IDNCT05687344

SponsorMedical College of Wisconsin

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-03

View on ClinicalTrials.gov More Hypertensive Disorder of Pregnancy trials