Evaluate the Effect of Nasal Spray in the Prevention of RTI in Children With Pre-school Wheezing

Inclusion Criteria: * Children diagnosed with wheezing * Patients aged between 3 and 6 years (inclusive) at the time of enrollment of both genders * Signature of the informed consent * Availability of a mobile phone capable of installing VIR@PP Exclusion Criteria: * Inability to adequately understand the Italian language * Presence of autoimmune pathologies, immunodeficiency, neuromuscular diseases, congenital cardiomyopathies, metabolic diseases * Presence of other syndromes and genetic pathologies * Patients on therapy with other drugs (steroids for topical and/or oral use) * Abnormalities of the nose or other conditions (e.g. severe hypotonia etc…) which make the administration of a nasal spray impossible or unsafe * Denial of informed consent * Participation in other clinical studies