UnknownNot Applicable

Assessment of Pain and Treatment Success After VPT Versus RCT in Mature Permanent Mandibular Molars With SIP: A RCT

44 participantsStarted 2023-02-26

Plain-language summary

Assessment of postoperative pain and treatment success after vital pulp therapy versus root canal treatment in mandibular molar with signs and symptoms of irreversible pulpitis. the null hypothesis, there is no difference will be observed in the pain level and treatment success between two treatments.

Who can participate

Age range

18 Years – 40 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Systemically healthy patients. * Patient's age range more than 15 years. * Mature permanent mandibular molars with deep caries. * Clinical diagnosis of symptomatic irreversible pulpitis. * Teeth with no need for the post. * Healthy periodontium and mobility within normal limits. * Patients who can understand the pain scale and can sign the informed consent Exclusion Criteria: * Teeth with a negative response to vitality testing. * Teeth with furcal bone loss. * Teeth with sinus tract * Teeth with swelling. * Teeth with a non-restorable crown. * Teeth with immature roots. * Teeth with no pulp exposure even after caries excavation. * History of analgesic intake in the previous week. * History of antibiotic intake in the previous month. * Insufficient bleeding after pulp exposure suggestive of partial necrosis of the pulp. * Inability to control bleeding within 10 min. * Radiographic evidence of external or internal root resorption vertical root fracture, perforation, calcification.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Postoperative pain

Timeframe: at 6 hours postoperative

Trial details

NCT IDNCT05681494

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-07-26

Contact for this trial

Amany IA mohamed, phd

01099300346 amany.ahmed@dentistry.cu.edu.eg

View on ClinicalTrials.gov More Symptomatic Irreversible Pulpitis trials