microRNAs in the Diagnosis of Atherosclerotic Plaque Instability

Inclusion criteria

• ✓. Availability of written informed consent to participate in research work;
• ✓. Age from 18 to 85 years;
• ✓. Availability of data from a general blood test, blood lipid profile (total cholesterol, very low density lipoproteins, low density lipoproteins, high density lipoproteins, triglycerides);
• ✓. Absence of clinical signs of atherosclerosis of brachiocephalic arteries (no stroke, transient ischemic attack. On auscultation of the carotid arteries, there are no additional noises);
• ✓. Absence of signs of atherosclerosis of the brachiocephalic arteries according to ultrasound duplex scanning (USDS) and/or multispiral computed tomography (MSCT) angiography of the brachiocephalic arteries;
• ✓. Conducted outpatient visit at a research center with clinical and biochemical blood tests performed, ultrasound examination of arterial vessels and/or multispiral tomography of arterial vessels with contrast enhancement and/or hospitalization at a research center.
• ✓. Chronic kidney disease stage 3b and above (glomerular filtration rate \< 45 ml / min / 1.73 sq.m);
• ✓. The presence of severe somatic pathology (with the exception of atherosclerosis of the carotid arteries and conditions caused by it), reducing life expectancy to less than 6 months;