Prospective Sibling Oocyte Study of a New Method to Improve Embryo Development in IVF/ICSI Patients

Female: Inclusion Criteria: * With ovarian reserve of between 8 and 30 antral follicles counting both ovaries * Treatment planned for embryo transfer at the blastocyst stage Exclusion Criteria: * Any diagnosed sexually transmitted infection (STI) * Diabetes or other metabolic disorders. * Recurrent pregnancy loss (defined as \>2 clinical pregnancies without live birth). * Previous failures in two or more IVF cycles Male: Inclusion Criteria for IVF: * Age: 20-55 years * Fresh sample (not cryopreserved ) * Sperm motility (TOTAL) ≥ 40% in spermogram * Normal sperm morphology (Kruger criteria) ≥ 4% in spermogram * Sperm count after swim up ≥ 5x10\^6 * Treatment planned for embryo transfer at the blastocyst stage Inclusion Criteria for ICSI: * Age: 20-55 years * Fresh sample (not cryopreserved ) * Sperm concentration ≥ 10x10\^6 /ml in spermogram * Sperm motility (TOTAL) ≥ 20% in spermogram * Normal sperm morphology (Kruger criteria) ≥ 3% in spermogram * Treatment planned for embryo transfer at the blastocyst stage Exclusion Criteria: * Any diagnosed sexually transmitted infection (STI) * Total failure of in vitro fertilization in previous cycles.