A prospective, exposure-control cohort study of older adults living with HIV comparing the neurological status of those who have had HIV infection for a longer period of time (long HIV group) to age, gender, and community-matched comparison group who have had HIV infection for a shorter period of time (short HIV group).
Age range
45 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Cognition - Zambian Mini-Mental Status Examination (zMMSE) - During enrollment
Timeframe: baseline/during enrollment
Cognition - Zambian Mini-Mental Status Examination (zMMSE) - on Year 1 of evaluation
Timeframe: Year 1 evaluation
Cognition - Zambian Mini-Mental Status Examination (zMMSE) - on Year 2 of evaluation
Timeframe: Year 2 evaluation
Cognition - International HIV Dementia Scale (I-HDS) - on Year 3 of evaluation
Timeframe: Year 3 evaluation
Cognition - International HIV Dementia Scale (I-HDS)- on Year 4 of evaluation
Timeframe: Year 4 evaluations
Cognition - International HIV Dementia Scale (I-HDS) - on Year 5 of evaluation
Timeframe: Year 5 evaluation
Cognition - International HIV Dementia Scale (I-HDS)- on Year 6 of evaluation
Timeframe: Year 6 evaluation
Mental Health - The Alcohol Use Disorders Identification Test (AUDIT) -Baseline/during enrollment
Timeframe: Baseline/during enrollment
Mental Health - The Alcohol Use Disorders Identification Test (AUDIT) - on Year 1 of enrollment
Timeframe: Year 1 evaluation
Mental Health - The Alcohol Use Disorders Identification Test (AUDIT)- on year 2 of evaluation
Timeframe: Year 2 evaluation
Mental Health - The Alcohol Use Disorders Identification Test (AUDIT) - on year 3 of evaluation
Timeframe: Year 3 evaluation
Mental Health - Center for Epidemiologic Studies Depression Scale (CES-D)- on year 4 of evaluation
Timeframe: Year 4 evaluation
Mental Health - Center for Epidemiologic Studies Depression Scale (CES-D)- on year 5 of evaluation
Timeframe: Year 5 evaluation
Mental Health - Center for Epidemiologic Studies Depression Scale (CES-D)- on year 6 of evaluation
Timeframe: Year 6 evaluation
Mental Health - The Generalized Anxiety Disorders Screen (GAD-7)- baseline/during enrollment
Timeframe: Baseline
Mental Health - The Generalized Anxiety Disorders Screen (GAD-7)- baseline/during enrollment
Timeframe: Baseline/during enrollment
Mental Health - The Generalized Anxiety Disorders Screen (GAD-7)- on year 1 of evaluation
Timeframe: Year 1 evaluation
Mental Health - The Generalized Anxiety Disorders Screen (GAD-7)- on year 2 of evaluation
Timeframe: Year 2 evaluation
Mental Health - The Generalized Anxiety Disorders Screen (GAD-7)- on year 3 of evaluation
Timeframe: Year 3 evaluation
Mental Health - The Generalized Anxiety Disorders Screen (GAD-7)- on year 4 of evaluation
Timeframe: Year 4 evaluation
Mental Health - The Generalized Anxiety Disorders Screen (GAD-7)- on year 5 of evaluation
Timeframe: Year 5 evaluation
Mental Health - The Generalized Anxiety Disorders Screen (GAD-7)- on year 6 of evaluation
Timeframe: Year 6 evaluation
Mental Health - An adaptation of the Harvard Trauma Questionnaire (HTQ)-baseline/during enrolment
Timeframe: Baseline/during enrollment
Mental Health - An adaptation of the Harvard Trauma Questionnaire (HTQ)- on year 1 of enrolment
Timeframe: Year 1 evaluation
Mental Health - An adaptation of the Harvard Trauma Questionnaire (HTQ)- on year 1 of evaluation
Timeframe: Year 2 evaluation
Mental Health - An adaptation of the Harvard Trauma Questionnaire (HTQ)- on year 3 of evaluation
Timeframe: Year 3 evaluation
Mental Health - An adaptation of the Harvard Trauma Questionnaire (HTQ)- on year 4 of evaluation
Timeframe: Year 4 evaluation
Mental Health - An adaptation of the Harvard Trauma Questionnaire (HTQ)- on year 5 of evaluation
Timeframe: Year 5 evaluation
Mental Health - An adaptation of the Harvard Trauma Questionnaire (HTQ) - on year 6 of evaluation
Timeframe: Year 6 evaluation
Frailty assessment - Body weight - baseline/during enrollment
Timeframe: Baseline/during enrollment
Frailty assessment - Body weight - on year 1 of evaluation.
Timeframe: Year 1 evaluation
Frailty assessment - Body weight- on year 2 of evaluation
Timeframe: Year 2 evaluation
Frailty assessment - Body weight - on year 3 of evaluation
Timeframe: Year 3 evaluation
Frailty assessment - Body weight on year 4 of evaluation
Timeframe: Year 4 evaluation
Frailty assessment - Body weight - on year 5
Timeframe: Year 5 evaluation
Frailty assessment - Body weight - on year 6 of evaluation
Timeframe: Year 6 evaluation
Frailty assessment - Body height- baseline/during enrollment
Timeframe: Baseline/during enrollment
Frailty assessment - Body height- on year 1 of evaluation
Timeframe: Year 1 of evaluation
Frailty assessment - Body height- on year 2 of evaluation
Timeframe: Year 2 of evaluation
Frailty assessment - Body height- on year 3 of evaluation
Timeframe: Year 3 of evaluation
Frailty assessment - Body height- on year 4 of evaluation
Timeframe: Year 4 of evaluation
Frailty assessment - Body height- on year 5 of evaluation
Timeframe: Year 5 of evaluation
Frailty assessment - Body height- on year 6 of evaluation
Timeframe: Year 6 of evaluation
Frailty assessment - Body mass index-baseline/during enrollment
Timeframe: Baseline/during enrollment
Frailty assessment - Body mass index- on year 1 of evaluation
Timeframe: Year 1 of evaluation
Frailty assessment - on year 2 of evaluation
Timeframe: Year 2 of evaluation
Frailty assessment - Body mass index- on year 3 of evaluation
Timeframe: Year 3 of evaluation
Frailty assessment - Body mass index- on year 4 of evaluation
Timeframe: Year 4 of evaluation
Frailty assessment - Body mass index- on year 5 of evaluation
Timeframe: Year 5 of evaluation
Frailty assessment - Body mass index- on year 6 of evaluation
Timeframe: Year 6 of evaluation
Frailty assessments - Grip strength- baseline/during enrollment
Timeframe: Baseline
Frailty assessments - Grip strength - on year 1 of evaluation
Timeframe: Year 1 evaluation
Frailty assessments - Grip strength- on year 2 of evaluation
Timeframe: Year 2 evaluation
Frailty assessments - Grip strength- on year 3 of evaluation
Timeframe: Year 3 evaluation
Frailty assessments - Grip strength- on year 4 of evaluation
Timeframe: Year 4 evaluation
Frailty assessments - Grip strength-on year 5 of evaluation
Timeframe: Year 5 evaluation
Frailty assessments - Grip strength- on year 6 of evaluation
Timeframe: Year 6 evaluation
Frail assessment - Physical Activity- baseline/during enrollment
Timeframe: Baseline
Frail assessment - Physical Activity- on year 1 of evaluation
Timeframe: Year 1 evaluation
Frail assessment - Physical Activity- on year 2 of evaluation
Timeframe: Year 2 evaluation
Frail assessment - Physical Activity- on year 3 of evaluation
Timeframe: Year 3 evaluation
Frail assessment - Physical Activity- on year 4 of evaluation
Timeframe: Year 4 evaluation
Frail assessment - Physical Activity- on year 5 of evaluation
Timeframe: Year 5 evaluation
Frail assessment - Physical Activity- on year 6 of evaluation
Timeframe: Year 6 evaluation
Frail assessment - Time Gait- baseline/during enrollment
Timeframe: baseline
Frail assessment - Time Gait- on year 1 of evaluation
Timeframe: Year 1 evaluation
Frail assessment - Time Gait- on year 2 of evaluation
Timeframe: Year 2 evaluation
Frail assessment - Time Gaiton year 3 of evaluation
Timeframe: Year 3 evaluation
Frail assessment - Time Gait- on year 4 of evaluation
Timeframe: Year 4 evaluation
Frail assessment - Time Gait- on year 5 of evaluation
Timeframe: Year 5 evaluation
Frail assessment - Time Gait- on year 6 of evaluation
Timeframe: Year 6 evaluation
Peripheral nerve health - Brief Peripheral Neuropathy (BPNS)- baseline/during enrollment
Timeframe: baseline/ during enrollment
Peripheral nerve health - Brief Peripheral Neuropathy (BPNS)- on year 1 of evaluation
Timeframe: Year 1 of evaluation
Peripheral nerve health - Brief Peripheral Neuropathy (BPNS)- on year 2 of evaluation
Timeframe: Year 2 evaluation
Peripheral nerve health - Brief Peripheral Neuropathy (BPNS)- on year 3 of evaluation
Timeframe: Year 3 evaluation
Peripheral nerve health - Brief Peripheral Neuropathy (BPNS)- on year 4 of evaluation
Timeframe: Year 4 evaluation
Peripheral nerve health - Brief Peripheral Neuropathy (BPNS)- on year 5 of evaluation
Timeframe: Year 5 evaluation
Peripheral nerve health - Brief Peripheral Neuropathy (BPNS)- on year 6 of evaluation
Timeframe: Year 6 evaluation
Peripheral nerve health - Heart Rate Variability(HRV)- baseline/during enrollment
Timeframe: Baseline/during enrollment
Peripheral nerve health - Heart Rate Variability(HRV)- on year 1 of evaluation
Timeframe: Year 1 evaluation
Peripheral nerve health - Heart Rate Variability(HRV) - on year 2 of evaluation
Timeframe: Year 2 evaluation
Peripheral nerve health - Heart Rate Variability(HRV)- on year 3 of evaluation
Timeframe: Year 3 evaluation
Peripheral nerve health - Heart Rate Variability(HRV)- on year 4 of enrollment
Timeframe: Year 4 evaluation
Peripheral nerve health - Heart Rate Variability(HRV)- on year 5 of evaluation
Timeframe: Year 5 evaluation
Peripheral nerve health - Heart Rate Variability(HRV)- on year 6 of evaluation
Timeframe: Year 6 evaluation