RecruitingNot Applicable

Genicular Nerve Block Versus Its Combination With Infiltration Between Popliteal Artery and Capsule of Posterior Knee

Egypt63 participantsStarted 2022-11-05

Plain-language summary

Comparison of the analgesic and physical recovery effect of genicular nerve block (GNB) alone and (GNB + infiltration between popliteal artery and posterior capsule of the knee (IPACK) in patients undergoing total knee replacement

Who can participate

Age range

21 Years – 60 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria: * Adult patients aged between 21 to 60 years * undergoing primary unilateral elective total knee arthroplasty under spinal anesthesia * Having informed consents * patients with physical status ASA I \& II * both genders * body mass index less than 40 kg/m2. Exclusion criteria * patients with Peripheral vascular disease * patients with history of allergy to local anesthesia or opioid analgesia, * those on anti-platelet, anticoagulant or B blocker drugs * Patients with acute decompensated heart failure * Patients with hypertension * Patients with heart block * Patients with coronary disease * Patients with bronchial asthma * Patients with bleeding disorders * Patients with compromised renal or hepatic function * pregnant female.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

2 hours visual analogue scale

Timeframe: at 2 hour postoperative.

4 hours visual analogue score

Timeframe: at 4 hours postoperative

6 hours visual analogue score

Timeframe: at 6 hours postoperative

8 hours visual analogue score

Timeframe: at 8 hours postopertaive

12 hours visual analogue score

Timeframe: at 12 hours postoperative

18 hours visual analogue score

Timeframe: at 18 hours postoperative

24 hours visual analogue score

Timeframe: at 24 hours postoperative

Trial details

NCT IDNCT05672784

SponsorZagazig University

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2024-12-05

Contact for this trial

Heba M Fathi, MD

01000143938 heba_elgendi@yahoo.com

View on ClinicalTrials.gov More Postoperative Pain trials