UnknownNot Applicable

Use of Airway Pressure Release Ventilation in Morbidly Obese Patients Undergoing Open Heart Surgery

Egypt60 participantsStarted 2022-12-03

Plain-language summary

The goal of this Randomized Clinical trial is to to investigate if the use of Air Pressure Release Ventilation in morbidly obese patients undergoing open heart surgery will improve post operative pulmonary outcomes 60 Patients will be randomized into two groups according to the mode of ventilation used into: Group A: airway pressure release ventilation (APRV) group (30 Patients) Group B: Standard (control) group (30 Patients) Post-operatively, Patients will be ventilated with conventional Synchronized Intermittent Mandatory Ventilation (SIMV) volume control mode

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age ≥18 y. * Scheduled for open heart Surgery with cardiopulmonary bypass (CPB) pump. * Class III Obesity (Morbid obesity): BMI ≥ 40.0 kg/m². Exclusion Criteria: * Patients with obstructive lung disease (asthma or chronic obstructive pulmonary disease). * Pneumothorax or Surgical emphysema. * Mechanical ventilation prior to the operation. * Patient Refusal.

What they're measuring

PO2/FIO2 (P/F) ratio

Timeframe: up to 3 days

Time of mechanical ventilation

Timeframe: up to 3 days

Trial details

NCT IDNCT05670483

SponsorAin Shams University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-05-03

Contact for this trial

Mohamed A. Alhadidy, MD

+201005092648 Mohamed_alaaeldin@med.asu.edu.eg

View on ClinicalTrials.gov More Pulmonary Atelectasis trials