CompletedNot Applicable

Decompressive Craniectomy in Patients With Cerebellar Infarction

72 participantsStarted 2016-01-05

Plain-language summary

The investigators aimed to evaluate the outcome in participants up to 80 years of age with space-occupying cerebellar infarction treated with suboccipital decompressive craniectomy (SDC) compared to medical therapy alone.

Who can participate

Age range

40 Years – 80 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * The presence of cerebellar territory infarction with an NIHSS score ≥8. * Initial Glasgow Coma Scale (GCS) score \<9 on admission and clinical deterioration (a score of ≥ 1 decrease on GCS score) within 48 hours from onset. * Decrease in the level of consciousness to a score of ≥ 1 on item 1a (level of consciousness) of the NIHSS, rapid deterioration to coma. Exclusion Criteria: * Prestroke mRS score ≥2. * Prestroke score on the Barthel Index \<95. * Score on the Glasgow Coma Scale ≤6. * Both pupils fixed and dilated. * Any other coincidental brain lesion that might affect outcome. * Space-occupying hemorrhagic transformation of the infarct. * Pregnancy. * Life expectancy \<3 years.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

The primary end point was survival with favorable outcome, defined as a score of 0 to 3 modified Rankin score

Timeframe: one year

Trial details

NCT IDNCT05670249

SponsorEge University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-12-25

View on ClinicalTrials.gov More Cerebellar Stroke trials

Who can participate

Age range

40 Years – 80 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.