The investigators will conduct an optimization trial among N=256 PWID newly started on medication for opioid use disorder and Pre-Exposure Prophylaxis (PrEP) to assess the performance of four intervention components (Attention, Executive Functioning, Memory, and Information Processing) aimed at enhancing the ability of PWID on MOUD to process and utilize HIV prevention content, leading to improvements in HIV prevention information, motivation, behavioral skills, and behaviors (IMB).
Age range
18 Years
Sex
ALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Pre-Exposure Prophylaxis Adherence via Dried Blood Spots (DBS)
Timeframe: PrEP adherence DBS measured at week 4
Pre-Exposure Prophylaxis Adherence via Dried Blood Spots (DBS)
Timeframe: PrEP adherence DBS measured at the 3-month post-intervention follow-up
Pre-Exposure Prophylaxis Adherence via Dried Blood Spots (DBS)
Timeframe: PrEP adherence DBS measured at the 6-month post-intervention follow-up
Pre-Exposure Prophylaxis Adherence via Dried Blood Spots (DBS)
Timeframe: PrEP adherence DBS measured at the 9-month post-intervention follow-up
Pre-Exposure Prophylaxis Adherence via pharmacy refill data
Timeframe: PrEP adherence pharmacy refill data measured at week 4
Pre-Exposure Prophylaxis Adherence via pharmacy refill data
Timeframe: PrEP adherence pharmacy refill data measured at the 3-month post-intervention follow-up
Pre-Exposure Prophylaxis Adherence via pharmacy refill data
Timeframe: PrEP adherence pharmacy refill data measured at the 6-month post-intervention follow-up
Pre-Exposure Prophylaxis Adherence via pharmacy refill data
Timeframe: PrEP adherence pharmacy refill data measured at the 9-month post-intervention follow-up
Pre-Exposure Prophylaxis Adherence via self-report scale
Timeframe: PrEP adherence pharmacy self report measured at week 4
Pre-Exposure Prophylaxis Adherence via self-report scale
Timeframe: PrEP adherence pharmacy self report measured at the 3-month post-intervention follow-ups
Pre-Exposure Prophylaxis Adherence via self-report scale
Timeframe: PrEP adherence pharmacy self report measured at the 6-month post-intervention follow-ups
Pre-Exposure Prophylaxis Adherence via self-report scale
Timeframe: PrEP adherence pharmacy self report measured at the 9-month post-intervention follow-ups