VR and Script Training of PWA (NCT05667480) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
VR and Script Training of PWA
Hong Kong26 participantsStarted 2023-04-10
Plain-language summary
The goal of this intervention study is to investigate the effects of immersive virtual reality in rehabilitation of language and communication of individuals with post-stroke aphasia. The main research questions are:
1. Is VR-based script training a feasible treatment to Cantonese-speaking PWA?
2. Will VR-based script training, when compared to conventional script training, better enhance treatment outcomes in functional communication of PWA?
Participants will be assessed before, in the middle of, immediately after treatment and 8-week post treatment in terms of their performance on:
1. Accuracy and time for producing trained scripts.
2. Accuracy and time for producing un-trained scripts
3. Standardized aphasia test on severity of language impairment
4. Standardized aphasia test on functional communication
The participants will be randomly allocated to receive one of the treatment:
1. Virtual reality-based computerized script training; or
2. Computerized script training without virtual reality Researchers will compare the treatment outcomes of the two treatment conditions and see if treatment with virtual reality would better promote outcomes when compared to training without virtual reality.
Who can participate
Age range
30 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. a stroke onset more than six months, with an Aphasia Quotient (AQ) below 96.4, as evaluated by the Cantonese version of Western Aphasia Battery (CAB; Yiu, 1992),
. premorbid fluent Cantonese speakers,
. aged between 30 and 80 years,
. no reported progressive neurogenic disorders such as dementia or Parkinson's disease,
. no motor speech disorders of moderate to severe level, and
. normal or corrected-to-normal vision and hearing functions
Exclusion criteria
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Percentage correct in reading aloud the sentences included in the trained scripts
Timeframe: From baseline up to 1-week post training
2
Time required in read aloud of trained scripts
Timeframe: From baseline up to 1-week post training
3
Percentage correct in spontaneous production of the sentences included in the trained scripts
Timeframe: From baseline up to 1-week post training
4
Time required for spantaneous production of trained scripts
Timeframe: From baseline up to 1-week post training
. concurrent participation in other aphasia treatment trials, and
. incompatibility with immersive VR exposure such as complains of nausea, headache, or other severe discomforts during trial use of a head-mounted device during screening.