The Avelle® Negative Pressure Wound Therapy System on Chronic Wounds

Inclusion Criteria: * Venous insufficiency as defined by CEAP Classification of C6 or C6R or Diabetic foot ulcer * Stalled wound/failed treatment in the opinion of the investigator. Defined as a wound that has not progressed by more than 30% in the previous 4 weeks * 1 qualifying wound which is amenable to NPWT * Reliable and available for follow-up * Low to moderate exudate * Able to tolerate negative pressure * \>18 years old at the time of consent * Able and willing to provide informed consent Exclusion Criteria: * Known sensitivities or allergies to components of the Avelle™ Negative Pressure Wound Therapy System * Necrotic wounds or wounds with eschar present * Wound is too small or too large based on wound dressing (\> 1cm2 and \< 100cm2) * Wound depth \>2cm * Use of DuoDERM® gel /petroleum gel/ creams/oil-based products * Active treatment for cancer or completed within the last 3 months * Severe malnutrition in the opinion of the investigator * Visible bone/tendon or exposed articular capsule * Exposed blood vessels * Clotting disorder * Malignant wounds * Systemic infection * Untreated osteomyelitis * Patients with HbA1c greater than 9 on Day 0 (Test to be performed within last 3 months) * Wounds greater than 12 months old * Previous failed NPWT within last 6 weeks on the qualifying wound * Active Pregnancy * Chronic Kidney Disease score of 5