CompletedNot Applicable

Awake Transnasal Laser-assisted Surgery (TNLS) and Microlaryngeal Surgery for Benign Laryngeal Lesions

Hong Kong60 participantsStarted 2021-05-01

Plain-language summary

This is a prospective, single-cluster randomised controlled trial conducted at two tertiary referral hospitals in Hong Kong to compare the clinical and functional outcomes of office-based transnasal laser-assisted surgery (TNLS) under local anesthesia to traditional microlaryngeal surgery (MLS) under general anesthesia.

Who can participate

Age range19 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * older than 18-year-old * mentally competent to give an informed consent * operable benign laryngeal lesions * able to tolerate transnasal flexible laryngoscopy Exclusion Criteria: * under 18-year old * unable to give an informed consent * unable to tolerate flexible laryngoscopy under local anesthesia * allergy to local anesthesia * unfavourable anatomy precluding adequate visualization * with extensive lesions with expected difficult operation * with pathologies suspicious of or confirmed malignancy

What they're measuring

Voice-Handicap Index (VHI-30)

Timeframe: Post-op 2 week

Voice-Handicap Index (VHI-30)

Timeframe: Post-op 6 week

Voice-Handicap Index (VHI-30)

Timeframe: Post-op 3 month

Voice-Handicap Index (VHI-30)

Timeframe: Post-op 6 month

Voice-Handicap Index (VHI-30)

Timeframe: Post-op 1 year

Trial details

NCT IDNCT05665829

SponsorChinese University of Hong Kong

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-12-01

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