A PiLot ClinicaL TrIal of ParicAlcitol for ChroNiC PancrEatitis

Inclusion Criteria: * Provision of signed and dated informed consent form * Stated willingness to comply with all study procedures and availability for the duration of the study * Male or female, aged 18-75 at time of enrollment * Diagnosis of Chronic Pancreatitis episode is not attributable to gallstones (i.e. suspected or definite biliary etiology), medications, trauma or autoimmune pancreatitis. * Ability to take oral medication and be willing to adhere to the dosing regimen * Normal Calcium levels- 8.5 to 10.2 mg/dL * Normal Phosphate levels- 2.8 to 4.5 mg/dL * Normal Parathyroid hormone levels- 10 to 65 pg/mL * For females of reproductive potential: use of highly effective contraception for at least 1 month prior to screening and agreement to use such a method during study participation and for an additional 1 week after the end of Investigational Product administration * For males of reproductive potential: use of condoms or other methods to ensure effective contraception with partner * No prior pancreatic surgery * Pancreatic necrosis, if present, is \<50% (to be verified by radiologist) * No involvement in any interventional trials currently or within 6 months of enrollment Exclusion Criteria: * Pregnancy or lactation * History of autoimmune or traumatic pancreatitis, or sentinel attack of acute necrotizing pancreatitis which results in suspected disconnected duct syndrome * Primary pancreatic tumors - pancreatic ductal adenocarcinoma, suspected cystic neoplasm (\>…