CompletedPhase 1/2

Remote Resistance Exercise Powering Survivors - Gastrointestinal Oncology

United States22 participantsStarted 2023-02-20

Plain-language summary

The purpose of the study is to evaluate a tele-resistance training exercise program for individuals undergoing chemotherapy for advanced upper gastrointestinal cancer.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age ≥ 18 years * Biopsy-proven upper GI cancer, stage III-IV * ECOG performance status 0-1 * Treatment plan of chemotherapy with planned return to Moffitt Cancer Center for restaging * Able to read and speak English fluently * Capable of providing informed consent Exclusion Criteria: * Regular engagement in RT (2x/week targeting all major muscle groups) * Screen failure for exercise safety based on Physical Activity Readiness Questionnaire (PAR-Q) and Patient-Reported Measurement Information System (PROMIS) screening questions * Underlying unstable cardiac or pulmonary disease or symptomatic cardiac disease (New York Heart Association functional class III or IV). * Recent fracture or acute musculoskeletal injury that precludes ability to participate in RT * Numeric pain rating scale of ≥ 7 out of 10 * Myopathic or rheumatologic disease that impacts physical function

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Percentage of Participants that Enroll and Consent - Enrollment Feasibility

Timeframe: Up to 36 Months

Percentage of Participants that Complete Study Assessments - Retention Feasibility

Timeframe: Up to 3 Months

Exercise Adherence - Feasibility

Timeframe: Up to 6 Months

Participant Evaluation of Feasibility and Acceptability - Acceptability

Timeframe: Up to 6 Months

Participant Self-Reported Musculoskeletal Injuries - Safety

Timeframe: Up to 6 Months

Participant Muscular Strength - Baseline

Timeframe: At Baseline

Participant Muscular Strength - Follow-up

Timeframe: Up to 6 Months

Trial details

NCT IDNCT05664178

SponsorH. Lee Moffitt Cancer Center and Research Institute

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-02-03

View on ClinicalTrials.gov More Gastrointestinal Cancer trials

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Percentage of Participants that Enroll and Consent - Enrollment Feasibility

Timeframe: Up to 36 Months

Percentage of Participants that Complete Study Assessments - Retention Feasibility

Timeframe: Up to 3 Months

Exercise Adherence - Feasibility

Timeframe: Up to 6 Months

Participant Evaluation of Feasibility and Acceptability - Acceptability

Timeframe: Up to 6 Months

Participant Self-Reported Musculoskeletal Injuries - Safety

Timeframe: Up to 6 Months

Participant Muscular Strength - Baseline

Timeframe: At Baseline

Participant Muscular Strength - Follow-up

Timeframe: Up to 6 Months