CompletedNot Applicable

Transversus Abdominis Plane Block Versus Ilioinguinal-Iliohypogastric Nerve Block for Postoperative Analgesia Following Open Total Abdominal Hysterectomy

Egypt42 participantsStarted 2022-11-01

Plain-language summary

The investigators hypothesised that ultrasound-guided transversus abdominis plane (TAP) block would prolong the time to first rescue nalbuphine within 24 hours compared with ultrasound-guided ilioinguinal-iliohypogastric (IIH) nerve block, by virtue of its broader dermatomal coverage (T10-L1 versus T12-L1) of the Pfannenstiel incision. This hypothesis direction was established before unblinding and data analysis.

Who can participate

Age range35 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Participants will be adult patients (35-65 years) * ASA I-III * Scheduled for elective open TAH Exclusion Criteria: * Patient refusal * BMI \> 40 kg·m-² * Pregnancy * Chronic pain requiring daily analgesics * Any known allergy to local anesthetic, nalbuphine, paracetamol, or diclofenac * Patients with neurological, psychological disorders or those lacking cooperation * Patients with anatomic abnormalities at site of injection, skin lesions or wounds at site of proposed needle insertion. * Patients with bleeding disorders defined as (INR \>2) and/ or (platelet count \<100,000/µL) * Patients with hepatic disease e.g. liver cell failure or hepatic malignancy or hepatic enlargement

What they're measuring

Time to first rescue nalbuphine within 24 hours

Timeframe: From end of surgery to first rescue dose within 24 hours postoperatively

Trial details

NCT IDNCT05656872

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-02-28

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