CompletedNot Applicable

Anesthesia Depth Increases Delirium Incidence

Germany130 participantsStarted 2015-09-01

Plain-language summary

This study aimed to determine whether targeting bispectral index (BIS) readings of 55 (light anaesthesia) was associated with a lower incidence of delirium, dementia (POD), POCD and mortality but higher rates of awareness and complications than a standard of care anaesthesia blinded to depth monitoring.

Who can participate

Age range70 Years – 110 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * scheduled for major surgery above 60 min duration * informed consent Exclusion Criteria: * emergency surgery with large blood loss and/or preoperative cardiovascular instability, scheduled regional or neuraxial anesthesia, language barriers with the unability to understand a German audio tape, unability or unwillingness to consent,hearing disabilities

What they're measuring

postoperative delirium by NUDESC

Timeframe: 6 to 24 months

postoperative dementia and cognitive deficit By MMSE and MAT Test

Timeframe: 6 to 24 months

awareness, memory function

Timeframe: 1 to 3 days postoperative

Trial details

NCT IDNCT05656703

SponsorHeidelberg University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-06-01

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