CompletedNot Applicable

The Antibiogram and Outcomes of Antimicrobial Regimens in Microbial Keratitis: A Prospective Cohort Study

Egypt123 participantsStarted 2021-12-31

Plain-language summary

This study is an observational prospective cohort study which aims to generate an antibiogram and to assess the clinical responses and outcomes of microbial keratitis patients, treated with empiric topical antimicrobial therapies, with the main objective being to recommend the most effective empiric therapy. Microbial keratitis patients are attending the Cornea Outpatient Clinic at Alexandria Main University Hospital, Alexandria, Egypt.

Who can participate

Age range1 Year – 90 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients diagnosed with bacterial keratitis either clinically or by culture. * Patients diagnosed with fungal keratitis either clinically or by culture. * Patients diagnosed with mixed bacterial and fungal keratitis either clinically or by culture. Exclusion Criteria: * Patients diagnosed with corneal abrasions and non-infectious corneal ulcers. * Patients diagnosed with acanthamoeba keratitis as a single causative agent. * Patients diagnosed with viral keratitis as a single causative agent. * Patients who are noncompliant to treatment.

What they're measuring

Corneal ulcer healing

Timeframe: 4 months from participation

The time to epithelialization

Timeframe: 4 months from participation

The antibiogram generation

Timeframe: 4 months from participation

Trial details

NCT IDNCT05655689

SponsorAlexandria University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2023-01-01

View on ClinicalTrials.gov More Bacterial Keratitis trials