Not Yet RecruitingNot Applicable

Remote Ischemic Conditioning Combined With Endovascular Stenting for Symptomatic Intracranial Atherosclerotic Stenosis

China160 participantsStarted 2023-01-01

Plain-language summary

The purpose of this registry is to evaluate the safety and efficacy of RIC for patients with symptomatic intracranial atherosclerotic stenosis (sICAS) undergoing endovascular therapy.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Patient admitted from Jan. 1st 2023 to Jan. 1st 2025;
. Age ≥ 18;
. Intracranial atherosclerosis stenosis measured as ≥70% by digital subtraction angiography or by other noninvasive methods, such as transcranial doppler, computed tomography angiography, or magnetic resonance angiography;
. A history of stroke/transient ischemic attack attributed to ICAS;
. Verbal and written informed consent is provided at the time of admission by patients or their legally authorized representatives.

Exclusion criteria

. Stenosis of other causes;
. Prior ipsilateral stroke with residual deficits;
. Uncontrolled hypertension (defined as systolic blood pressure ≥200 mm Hg despite medications at enrollment);
. Peripheral vascular disease (especially subclavian arterial and upper limb artery stenosis or occlusion).

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

The presence of ≥1 new brain lesions on DWI within 48 hours after endovascular stenting

Timeframe: 48 hours

Incidence of clinical adverse events within 12 months after endovascular stenting

Timeframe: 12 months

Trial details

NCT IDNCT05653505

SponsorTianjin Huanhu Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-01-01

Contact for this trial

Ming Wei, PhD

13502182903 drweiming@163.com

View on ClinicalTrials.gov More Intracranial Arteriosclerosis trials