WithdrawnPhase 2/3

Prolonged Intravenous Therapy Versus Early Initiation of an Oral Loop Diuretic in Decompensated Heart Failure

Stopped: no recruitment

Poland0Started 2022-12-07

Plain-language summary

The goal of this clinical study is to compare treatment regimens of loop diuretics in patients with decompensated heart failure. The main aim is to answer if early change from intravenous to oral loop diuretics is safe and effective.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. Fluid Retention Features:
✓. The concentration of natiuretic peptides must be assessed within 24 hours of admission to the hospital and be:
✓. Exacerbation of heart failure treated with at least 40 mg of furosemide IV. (or 20 mg torasemide equivalent)
✓. Left ventricular ejection fraction \< 50% (assessed and documented in the last 12 months prior to study entry)
✓. Age \>= 18 years
✓. The study participant gave and signed an informed consent to participate in the study. No medical procedure related to the study was performed prior to giving informed consent.

What they're measuring

number of patients requiring hospitalization

Timeframe: 12 weeks

Time to hospitalization measured in days

Timeframe: Up to 12 weeks

Trial details

NCT IDNCT05652322

SponsorJan Kochanowski University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-12-01

View on ClinicalTrials.gov More Heart Failure trials