Active — Not RecruitingNot Applicable

The CALERIE™ Legacy Study

United States216 participantsStarted 2023-04-06

Plain-language summary

The purpose of the CALERIE Legacy Study is to follow up on the health and wellness of participants from phase 2 of the Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy (CALERIE) trial, which was conducted from 2007 to 2011.

Who can participate

Age range33 Years – 70 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Enrolled in the CALERIE trial and started their allocated group (CR intervention or ad libitum control condition) * Willing and able to attend one of the clinical sites for an in-person visit and provide informed consent Exclusion Criteria: * Pregnant women * Women less than 12 months postpartum * Documented note from the CALERIE trial indicating that the subject should not be contacted or requested not to be contacted for future research * Diagnosed active cancer or terminal illness

What they're measuring

Biological age - Klemera-Doubal Method

Timeframe: 10-15 years post CALERIE trial

Healthspan

Timeframe: 10-15 years post CALERIE trial

Trial details

NCT IDNCT05651620

SponsorTufts University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-03-31

View on ClinicalTrials.gov More Calorie Restriction trials