Enamel Abrasion and Stain Removal Efficacy of Two Whitening Toothpastes: An In-vitro and In-vivo Trial

IN VIVO: Patients inclusion: * Adult male and female patients ≥18 years. * Good oral and general health and oral hygiene have at least eight natural anterior teeth (incisors and canines) assessable for extrinsic stain and be available for all study appointments. Patients exclusion: * Uncooperative behavior. * Patients allergic to tooth paste material. * Patient with history of medical disease, drug therapies or any other serious relevant problem. * Pregnant or breastfeeding women. * Patients with fixed orthodontic appliances * Patients who had professional tooth whitening, within the last six months. * Patients who had significant amounts of calculus on facial surfaces of the incisors/canines. * Patients who had undergone professional periodontal treatment within the previous six months or used mouth rinses for the treatment/ control of a periodontal condition. * Patients who had advanced periodontal disease on anterior teeth. * Xerostomic patients. * Patients who used medications which could affect saliva flow or cause staining. * Patients who had undergone dental prophylaxis within 8 weeks of screening. * Patients who used minocycline or doxycycline within 30 days of screening or between screening and baseline. Tooth inclusion: ▪ Vital anterior maxillary and mandibular teeth free of caries or restorations, no cervical lesions and no periodontal disease. Tooth exclusion: * Intrinsically Discolored teeth caused by tetracycline, fluorosis, hypocalcification hyperplasia…