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CSF Biomarkers in Idiopathic Intracranial Hypertension

Egypt50 participantsStarted 2021-12-01

Plain-language summary

Aim of the study is to high lighten the rule of CSF biomarkers in early diagnosis of IIH and in follow up to reach to a definite clinically based decision if this patient will improved on medical treatment or that patient is in need for surgical intervention.

Who can participate

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: \- 1. All patients with signs and symptoms of increased intracranial pressure (headaches, nausea, vomiting, transient visual obscurations, papilledema). 2\. CSF opening pressure \>25 cm water with normal CSF composition. Exclusion Criteria: * 1\. localizing neurologic signs, except for unilateral or bilateral sixth cranial nerve palsy. 2\. Evidence of hydrocephalus, mass, infection, structural, or vascular lesion (including venous sinus thrombosis) on imaging. 3\. Patients with IIH who undergo surgical intervention (thecoperitoneal shunt or optic nerve fenestration) 4. Other identified causes of increased ICP.

What they're measuring

Relation between lumper puncture opening pressure and specific biomarkers

Timeframe: Baseline

Relation between lumper puncture opening pressure and visual disturbance

Timeframe: 3 days

Trial details

NCT IDNCT05647837

SponsorAssiut University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-11-20

Contact for this trial

Ebrahim A Yousuf, master

01118550865 Ebrahim.20133765@med.au.edu.eg

View on ClinicalTrials.gov More Intracranial Hypertension trials