RecruitingNot Applicable

ImpACt of Very High Protein Content Enteral nUtrition Formulas on Critically Ill MUltipLe trAuma paTiEnts

Romania70 participantsStarted 2023-03-01

Plain-language summary

This prospective observational randomized study aims to determine energy, protein intake and gastrointestinal tolerance while using enteral nutrition formulas with very high protein content and enteral nutrition formulas with normal protein content. * Differences regarding achieving protein and calorie daily targets when using enteral nutrition formulas with different protein content * Differences regarding residual gastric volume when using enteral nutrition formulas with different protein content * Differences regarding body composition when using enteral nutrition formulas with different protein content

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adult patients (\>18 yrs) admitted to the ICU * Multiple trauma (Injury severity score \> 18) * Intubation and mechanical ventilation upon admission in ICU or during the first 24 hours of admission, for at least 48 h Exclusion Criteria: * Age \< 18 years * Pregnant women * Patients not intubated or not mechanically ventilated or receiving only non-invasive ventilation * Patients with enteral feeding contraindication 48 h after admission * Patients with recent gastrointestinal surgical intervention * Patients on chronic therapy with corticosteroids

What they're measuring

Calorie and protein target

Timeframe: on day 5 days

Calorie and protein target

Timeframe: on day 10

Trial details

NCT IDNCT05647135

SponsorRomanian Society for Enteral and Parenteral Nutrition

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-12-01

Contact for this trial

Ioana Grintescu, MD, PhD

+40722329187 ioana.grintescu@rospen.ro

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