Effect of Combined Antioxidant Therapy on Oxidative Stress Markers and Inflammatory Cytokines in Patients With Tinnitus

Inclusion Criteria: * Male or female with subjective chronic tinnitus (unilateral or bilateral) * Patients with normal audiometry or identification of hearing loss up to a medium degree (20-70 dB) * Patients with evidence of endotic tinnitus * Patients who have or do not have social medical security * Females of childbearing age with a negative pregnancy test and use of oral contraceptives * Patients under pharmacological management with a period of stable medication (≥3 months) for chronic degenerative diseases and under good metabolic control (according to ADA 2022 criteria) through primary intervention Exclusion Criteria: * Presence of tinnitus secondary to head trauma, acoustic trauma, or sudden hearing loss * History or presence of Ménière's disease, otosclerosis, acute or chronic otitis media * Active gastrointestinal haemorrhagic disease * History or presence of cancer (any type) or submission to radio and/or chemotherapy * Autoimmune disease (any) * History of severe cardiovascular disease (myocardial infarction, stroke, severe peripheral vascular disease) * Benign prostatic hyperplasia * Blood dyscrasias and/or bleeding diathesis * Thyroid disease (any) * Temporomandibular joint dysfunction * Neurodegenerative processes * Hepatic and renal failure * Closed or open angle glaucoma * Intake of any medication belonging to the following families (Anticoagulants, Benzodiazepines, ASA diuretics, Aminoglycosides, Chemotherapeutics, Acetylsalicylic Acid, Quinine, MAOIs) * …