Active — Not RecruitingNot Applicable

MAnagement of Systolic Blood Pressure During Thrombectomy by Endovascular Route for Acute Ischaemic STROKE

Australia, New Zealand550 participantsStarted 2019-11-28

Plain-language summary

Stroke is the third most common cause of death in New Zealand and is one of the leading causes of long-term disability at all ages. A life-saving clot retrieval procedure can save lives and prevent disability of patients with ischaemic stroke who get to hospital in time. In New Zealand, 90% of clot retrieval procedures are performed under general anaesthesia. Many anaesthetic drugs can affect blood pressure (BP) and blood flow within the brain. Increasing BP during the procedure could provide additional benefits in this devastating disease. A large trial is needed to investigate BP management during clot retrieval.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. 'wake up' stroke; CT with no (or at most minimal) acute infarction or
✓. patient 80 years or older (NIHSS of 10 and infarct volume less than 21 ml on DWI or CT perfusion-CBF)
✓. patient less than 80 years (NIHSS of 10 and infarct volume less than 31 ml on DWI or CT perfusion-CBF NIHSS of 20 and infarct volume less than 51 ml on DWI or CT perfusion-CBF).

What they're measuring

Day 90 Modified Rankin Score

Timeframe: 90 days Post Thrombectomy

Trial details

NCT IDNCT05645861

SponsorAuckland City Hospital

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2026-01-31

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