RecruitingNot Applicable

Vaginal Microbiome and HPV Pre-malignant and Cervical Dysplasia

Israel90 participantsStarted 2022-11-09

Plain-language summary

In this study, the investigators will prospectively collect, analyze and integrate information regarding vaginal microbiome composition and HPV presence in women with cervical pathologies (high-grade CIN and CC) and controls, to construct a large dataset from patients with pre-cancerous cervical lesions and healthy women, to evaluate the personalized contribution of the vaginal microbiome to the CIN-CC sequence.

Who can participate

Age range25 Years – 70 Years

SexFEMALE

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Inclusion Criteria: * Age 25-70 * Attended the clinic for a Pap smear or colposcopy Exclusion Criteria: * Patient does not approve sample collection * Usage of antibiotics in the month prior to clinic visit * Usage of any vaginal preparation or medication in the week prior to sample collection (anti-fungal, spermicides, lubricant etc.) * Menstruation * Pregnancy

What they're measuring

Characterization of the microbiome using molecular methods.

Timeframe: 1 year

Trial details

NCT IDNCT05640700

SponsorHadassah Medical Organization

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-12-30

Contact for this trial

Ahinoam Lev Sagie, MD

+972-54-4327178 levsagie@netvision.net.il

View on ClinicalTrials.gov More Human Papilloma Virus trials