Ultrasound-guided Femoral Puncture to Reduce Access- Related Complications After TAVR: (ACCESS-TAVR SIRIO)

Inclusion Criteria: * Eligible Patients are male or female with severe aortic stenosis evaluated by the Heart Team as candidate to TAVR based on the current cardiology guidelines. Exclusion Criteria: * Refusal to participate in the study; * Inability to provide written consent to the study protocol; * Chronic immuno-suppressant therapy; * Any concomitant condition which, in the opinion of the Investigator, would not allow safe participation in the study (e.g., drug addiction, alcohol abuse, emotional/psychological disorder); * Enrolment in another study that could confound the results of this study; * Life expectancy \< 1 year; * Any contraindication to TAVR procedure; * Non transfemoral TAVR.