CompletedNot Applicable

Long Term Renal Function After CRRT in the Paediatric Intensive Care Unit, a Follow-up Study.

Sweden156 participantsStarted 2022-01-20

Plain-language summary

In this study the investigators will evaluate the long-term renal function in children treated with continuous renal replacement therapy (CRRT) due to acute kidney injury (AKI) and multiple organ failure (MOF) in the pediatric intensive care unit (PICU). These children are not always referred for nephrology follow up after their ICU stay and it is unclear to what extent the patients suffer from chronic renal disease. The primary aim is to establish the frequency of chronic kidney disease (CKD) in children treated with CRRT due to AKI. Secondary outcomes will include mortality, frequency of end stage-renal disease (ESRD) and need for hemodialysis and/or renal transplantation.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: \- Age newborn to 18 when admitted to ICU. CRRT treatment 2008-2021 due to AKI stage ≥ stage 1 (according to KDIGO) and/or ≥ 2 organ failures Exclusion Criteria: * CRRT due to metabolic and/or endocrinologic comorbidity. * Chronic renal failure before CRRT. * Previous renal transplantation. Prospective part: \- Not a resident of Stockholm County and no planned follow up at Karolinska University Hospital. Retrospective part: \- Patient referred to Karolinska University Hospital from a hospital outside Sweden.

What they're measuring

Chronic renal disease (CKD)

Timeframe: Up to12 years.

Chronic renal disease (CKD)

Timeframe: Up to 12 years

Trial details

NCT IDNCT05629273

SponsorRegion Stockholm

Sponsor typeOTHER_GOV

Study typeOBSERVATIONAL

Primary completion2024-10-12

View on ClinicalTrials.gov More Acute Kidney Injury trials