UnknownNot Applicable

Carotid Revascularization Versus Best Medical Treatment for Asymptomatic Carotid Stenosis

China1,056 participantsStarted 2022-10-14

Plain-language summary

This is a multicenter, open, randomized controlled trial to evaluate the efficacy and safety of carotid artery stenting/carotid endarterectomy versus best medical treatment for asymptomatic carotid artery stenosis in Chinese population.

Who can participate

Age range40 Years – 80 Years

SexALL

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Inclusion criteria

✓. Age 40-80 years;
✓. Carotid artery stenosis 50%-90% (ultrasound, CT, or DSA);
✓. Asymptomatic carotid stenosis, that is, no transient ischemic attack, stroke, or other neurological symptoms in the past 6 months;
✓. Patients who could complete 12 months of follow-up;
✓. Patients who signed informed consent forms.

Exclusion criteria

✕. Patients who had a TIA, stroke, or other related neurological symptoms within the previous 6 months;
✕. Patients with spontaneous intracerebral hemorrhage in the past 12 months；
✕. Patients with large intracranial aneurysms (diameter\> 5mm)，and cannot be treated in advance or contemporaneous;
✕. Chronic total occlusion without obvious cerebral ischemia symptoms；
✕. Patients with neurologic disorder that caused transient or permanent neurological deficits and can not be identified with transient ischemic attack or stroke；
✕. Patients with severe dementia;
✕. Common carotid artery opening lesion；
✕. Severe intracranial stenosis in tandem;

What they're measuring

Any Periprocedural Stroke, Myocardial Infarction, or Death During1 month Peri-procedural Period, and Postprocedural Ipsilateral Stroke 1 to 12-months.

Timeframe: 0 to 12 months

Trial details

NCT IDNCT05623904

SponsorXuanwu Hospital, Beijing

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-12

Contact for this trial

Yongquan Gu, Dr.

+8615901598209 gu15901598209@aliyun.com

View on ClinicalTrials.gov More Carotid Artery Stenting trials