Comparing the Safety and Effectiveness of Tunnel PICC Guided by EDUG and Conventional PICC (NCT05621473) | Clinical Trial Compass
UnknownNot Applicable
Comparing the Safety and Effectiveness of Tunnel PICC Guided by EDUG and Conventional PICC
420 participantsStarted 2022-12-01
Plain-language summary
This study was designed as a prospective, multicenter, randomized controlled study, with the incidence of postoperative complications as the main observation end point. It was a superiority design.The purpose of this study was to compare the incidence of complications associated with EDUG-guided subcutaneous tunneling and conventional puncture after peripheral vein placement of PICCs
Who can participate
Age range18 Years
SexALL
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Inclusion Criteria:
* Age ≥18 years old;
* Immunocompromised patients, including:
① Patients with congenital T cell/B cell deficiency or macrophage disorder;
② Patients with solid malignant tumors or hematological malignancies;
③ Patients with AIDS;
④ Patients undergoing splenectomy or solid organ transplantation;
⑤ Patients with rheumatic diseases and treated with immunomodulatory drugs;
* Follow the doctor's advice to perform PICC catheterization for the first time;
* No serious cardiovascular disease, such as atrial fibrillation, pulmonary heart disease, severe conduction block, etc., before catheter placement;
* Patients who have not participated in other clinical studies;
* Patients who voluntarily participate in the clinical study and can cooperate with the clinical follow-up.
Exclusion Criteria:
* Known allergy to catheter material;
* History of infection, injury or radiation therapy at the puncture site;
* There is a history of venous thrombosis or surgical operation at the puncture site;
* Severe abnormal coagulation function;
* Superior vena cava compression syndrome;
* Radical mastectomy for breast cancer or axillary lymph node dissection on the operative side of the limb;
* Pacemaker and arteriovenous fistula ipsilateral limb.