CompletedNot Applicable

CBD, Nutrient Metabolism and Energy Intake

United Kingdom15 participantsStarted 2021-09-30

Plain-language summary

CBD may affect metabolic control and energy intake. However, there is currently little data regarding these specific outcomes in humans. Therefore, this study will investigate whether a single 300 mg dose of CBD can improve metabolic control following a meal and/or reduce energy intake at a subsequent meal. Healthy, adult volunteers will complete two conditions in a crossover design, comparing outcomes following both CBD and placebo supplementation.

Who can participate

Age range18 Years – 50 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: • Self-report as healthy, male or female, aged 18-50, body mass index ≥18.5 and \<30.0 Exclusion Criteria: * Currently engage in \>10 hours moderate or vigorous intensity physical activity per week * Have consumed CBD or cannabis at all within the past two months * Have used CBD or cannabis regularly (\>2x in a week) within the past four months * Are suffering from any clinically significant illness * Have regularly used tobacco within the previous 6 months (\> 2/week) * Currently use any prescription or over-the-counter medications (except for hormonal contraception and simple painkillers) * Have given a standard blood donation within 30 days of screening * Are currently pregnant or lactating * Are allergic/intolerant to any ingredients in food items provided during the study

What they're measuring

Energy intake

Timeframe: ~5-30 minutes (time taken to eat a single meal)

Postprandial Glycaemia

Timeframe: 3 hours

Postprandial Triglyceridaemia

Timeframe: 3 hours

Trial details

NCT IDNCT05618756

SponsorLoughborough University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-04-30