Comparison of 68Ga-FAPI-46 PET and 18F-FDG PET in Lung Cancer (NCT05617742) | Clinical Trial Compass
CompletedNot Applicable
Comparison of 68Ga-FAPI-46 PET and 18F-FDG PET in Lung Cancer
Taiwan58 participantsStarted 2022-12-01
Plain-language summary
This is a prospective, single-center, single arm, open label study to evaluate the performance of 68Ga-FAPI-46 for the diagnosis of primary and metastatic lesions of lung cancer with comparison to 18F-FDG PET.
Who can participate
Age range
20 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Age \> 20 years
. Informed consent obtained from patients and families
. Patients with histology confirmed lung cancer or patients with GGO on chest CT planned to have biopsy or surgery
. Patients scheduled to undergo FDG-PET examination
. Performance status: 0, 1, 2, 3
Exclusion criteria
. Contraindication to FAPI-PET and FDG-PET such as pregnant, or lactating patients
. Patients with mainly malignant pleural effusion without other measurable lesions
. Undergoing irradiation at accrual
. Active infection or other serious underlying medical conditions not compatible with study entry
. History of significant neurological or psychiatric disorders including dementia that would prohibit the understanding and giving of informed consent
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
To define the diagnostic performance 68Ga-FAPI PET