Cyclopol on Electrophysiological Monitoring During Spine Surgery: a Randomized Controlled, Noninf… (NCT05617690) | Clinical Trial Compass
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Cyclopol on Electrophysiological Monitoring During Spine Surgery: a Randomized Controlled, Noninferiority Study
China148 participantsStarted 2023-04-04
Plain-language summary
Postoperative visual function injury occurs after spinal cord, neurosurgery, ophthalmology and other operations, which directly affects the postoperative quality of life of patients. Flash visual evoked potential (FVEP) is important for evaluating visual function under general anesthesia during operation. The changes of visual function can be observed and recognized in time through the amplitude changes of FVEP, which can avoid or reduce the visual function damage during operation. Anesthesia method determines the success and variability of electrophysiological monitoring to a certain extent. The purpose of this study is to investigate the effect of total intravenous anesthesia based on cyclopol on FVEP compared with propofol.
Who can participate
Age range18 Years – 65 Years
SexALL
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Inclusion criteria
✓. Patients undergoing elective spinal surgery under general anesthesia;
✓. Intraoperative electrophysiological monitoring is required;
✓. 18-65 years old;
✓. ASA I-III;
✓. Sign the informed consent.
Exclusion criteria
✕. Patients with visual impairment;
✕. Patients with severe liver or kidney disease;
✕. Uncontrolled hypertension, diabetes, severe arrhythmia or unstable angina pectoris;
✕. Have mental illness or unable to communicate;