Mirabegron 25 mg for Treatment of Primary Nocturnal Enuresis

Inclusion Criteria: * primary nocturnal enuresis, * negligible daytime wetting, * wet at least 4 times over 4 weeks * normal clinical examination with no neurological or urological cause for the enuresis Exclusion Criteria: * secondary enuresis, polysymptomatic * neurologic bladder, neurological disorders, * urinary incontinence disorders * previous anti NE drugs.