Active — Not RecruitingNot Applicable

A Comparison of Contact Aspiration Versus Stent Retriever for Acute Basilar Artery Occlusion

China338 participantsStarted 2022-11-07

Plain-language summary

Compare the effectiveness and safety of contact aspiration (CA) and stent retriever (SR) in acute ischemic stroke patients with basilar artery occlusion.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. Age≥18 years;
✓. Acute basilar artery occlusion confirmed by CTA/MRA/DSA;
✓. Last known well to puncture time≤24 hours;
✓. pc-ASPECTS score≥6 points;
✓. Baseline NIHSS score≥10 points;
✓. Consent to endovascular treatment;
✓. Informed consent signed.

Exclusion criteria

✕. Baseline mRS≥3 points;
✕. Known or suspected severe basilar artery stenosis (\>70%) or chronic occlusion based on history, imaging, or clinical manifestations;
✕. Refractory hypertension that is difficult to be controlled by drugs (defined as persistent systolic blood pressure \>185 mmHg or diastolic blood pressure \>110 mmHg)
✕. Genetic or acquired hemorrhagic tendency, coagulation factor deficiency or on anticoagulant therapy and International Normalized Ratio (INR) \> 3.0;
✕. Laboratory tests: baseline blood glucose \<50mg/dl (2.8mmol/L) or \>400mg/dl (22.2mmol/L); Baseline platelet count \<50×109/L;
✕. Known severe allergy (more severe than skin rash) to contrast agents uncontrolled by medications;
✕. Females who are pregnant, or those of childbearing, potential with positive urine or serum beta Human Chorionic Gonadotropin test;
✕. Other circumstances that the investigator considers inappropriate for participation in the trial or that may pose significant risks to patients (such as inability to understand and/or follow the study procedures and/or follow up due to mental disorders, cognitive or emotional disorders).

What they're measuring

Rate of first pass effect (FPE)

Timeframe: 24 hours

Trial details

NCT IDNCT05615038

SponsorBeijing Tiantan Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-02-21

View on ClinicalTrials.gov More Basilar Artery Occlusion trials