The proposed research is an important extension of an ongoing perioperative personalized analgesia and intravenous opioid pharmacogenetic research. This research focuses on two of the most commonly used oral opioid analgesics, oxycodone, and methadone in elderly adults undergoing cardiac surgery.
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Determine Genetic Factors - Opioid Related Adverse Events (RD)
Timeframe: Immediately post-surgery during hospital stay
Determine Genetic Factors - Opioid Related Adverse Events (PONV)
Timeframe: Immediately post-surgery during hospital stay
Determine Genetic Factors - Opioid Related Adverse Events (Excessive Sedation)
Timeframe: Immediately post-surgery during hospital stay
Determine Genetic Factors - Uncontrolled severe pain
Timeframe: Immediately post-surgery during hospital stay