Active — Not RecruitingNot Applicable

Herpes Virus Infections in Kidney Transplant Patients

Denmark280 participantsStarted 2023-01-01

Plain-language summary

Kidney transplant recipients are at increased risk of infections, including Varicella-zoster virus (VZV) infections. Vaccination against VZV is routinely offered to all kidney transplant recipients and candidates in Denmark. In this exploratory observational study, the VZV specific immune response in kidney transplant candidates and recipients will be characterized at different time points in relation to transplantation, vaccination and infections. More knowledge on the immune reaction to transplantation, VZV vaccination and VZV infections may provide improved strategies for prevention and treatment of VZV infections in kidney transplant candidates and recipients.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Kidney transplant recipient transplanted after 2019-01-01 OR on the kidney transplant waitlist * Has been offered Shingrix® vaccination Exclusion Criteria: * Lack of informed consent * Inability to understand the study information

What they're measuring

Change in levels of antibodies against Varicella-Zoster virus

Timeframe: 12 months

Change in presence and function of Varicella-Zoster virus-specific T cells

Timeframe: 12 months

Trial details

NCT IDNCT05604911

SponsorSusanne Dam Nielsen, MD, DMSc

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-02-01

View on ClinicalTrials.gov More Kidney Transplant; Complications trials